Downregulation of thioredoxin-1-dependent CD95 S-nitrosation by Sorafenib reduces liver cancer

Downregulation of thioredoxin-1-dependent CD95 S-nitrosation by Sorafenib reduces liver cancer

Hepatocellular carcinoma (HCC) represents 80% of the primary hepatic neoplasms. It is the sixth most frequent neoplasm, the fourth cause of cancer-related death, and 7% of registered malignancies. Sorafenib is the first line molecular targeted therapy for patients in advanced stage of HCC. The prese...

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Bibliographic Details
Main Authors: Raúl González, María A. Rodríguez-Hernández, María Negrete, Kalina Ranguelova, Aurelie Rossin, Carmen Choya-Foces, Patricia de la Cruz-Ojeda, Antonio Miranda-Vizuete, Antonio Martínez-Ruiz, Sergio Rius-Pérez, Juan Sastre, José A. Bárcena, Anne-Odile Hueber, C. Alicia Padilla, Jordi Muntané
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:Redox Biology
Subjects:
Apoptosis
Cell proliferation
CD95
GSNOR
Hepatocarcinoma
Nrf2
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231720304882

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http://www.sciencedirect.com/science/article/pii/S2213231720304882

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