Apelin signaling drives vascular endothelial cells toward a pro-angiogenic state

Apelin signaling drives vascular endothelial cells toward a pro-angiogenic state

To form new blood vessels (angiogenesis), endothelial cells (ECs) must be activated and acquire highly migratory and proliferative phenotypes. However, the molecular mechanisms that govern these processes are incompletely understood. Here, we show that Apelin signaling functions to drive ECs into su...

Full description

Bibliographic Details
Main Authors: Christian SM Helker, Jean Eberlein, Kerstin Wilhelm, Toshiya Sugino, Julian Malchow, Annika Schuermann, Stefan Baumeister, Hyouk-Bum Kwon, Hans-Martin Maischein, Michael Potente, Wiebke Herzog, Didier YR Stainier
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-09-01
Series:eLife
Subjects:
apelin
notch
metabolism
angiogenesis
endothelial cells
sprouting
Online Access:https://elifesciences.org/articles/55589

Internet

https://elifesciences.org/articles/55589

Similar Items