3D-Hepatocyte Culture Applied to Parasitology: Immune Activation of Canine Hepatic Spheroids Exposed to <i>Leishmania infantum</i>

3D-Hepatocyte Culture Applied to Parasitology: Immune Activation of Canine Hepatic Spheroids Exposed to <i>Leishmania infantum</i>

The application of innovative three-dimensional (3D) spheroids cell culture strategy to Parasitology offers the opportunity to closely explore host–parasite interactions. Here we present a first report on the application of 3D hepatic spheroids to unravel the immune response of canine hepatocytes ex...

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Bibliographic Details
Main Authors: Armanda V. Rodrigues, Graça Alexandre-Pires, Ana Valério-Bolas, David Santos-Mateus, Mariana Rafael-Fernandes, Maria A. Pereira, Dário Ligeiro, Telmo Nunes, Raquel Alves-Azevedo, Marcos Santos, Isabel Pereira da Fonseca, Gabriela Santos-Gomes
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Biomedicines
Subjects:
3D cell culture
hepatocytes
immune response
<i>Leishmania infantum</i>
meglumine antimoniate
Online Access:https://www.mdpi.com/2227-9059/8/12/628

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https://www.mdpi.com/2227-9059/8/12/628

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