Fractalkine is expressed in early and advanced atherosclerotic lesions and supports monocyte recruitment via CX3CR1.

Fractalkine (CX3CL1, FKN) is expressed in the inflamed vascular wall and absence of FKN reduces atherogenesis. Whether FKN is expressed throughout all stages of atherosclerotic disease and whether it directly contributes to monocyte recruitment to atherosclerotic lesions is not known. We collected h...

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Main Authors: Moritz Stolla, Jaroslav Pelisek, Marie-Luise von Brühl, Andreas Schäfer, Verena Barocke, Peter Heider, Michael Lorenz, Anca Tirniceriu, Alexander Steinhart, Johann Bauersachs, Paul F Bray, Steffen Massberg, Christian Schulz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3423360?pdf=render