Neurons are the Primary Target Cell for the Brain-Tropic Intracellular Parasite Toxoplasma gondii.

Toxoplasma gondii, a common brain-tropic parasite, is capable of infecting most nucleated cells, including astrocytes and neurons, in vitro. Yet, in vivo, Toxoplasma is primarily found in neurons. In vitro data showing that interferon-γ-stimulated astrocytes, but not neurons, clear intracellular par...

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Bibliographic Details
Main Authors: Carla M Cabral, Shraddha Tuladhar, Hans K Dietrich, Elizabeth Nguyen, Wes R MacDonald, Tapasya Trivedi, Asha Devineni, Anita A Koshy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-02-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4760770?pdf=render