A closer look into NADPH oxidase inhibitors: Validation and insight into their mechanism of action

A closer look into NADPH oxidase inhibitors: Validation and insight into their mechanism of action

NADPH-oxidases (NOXs) purposefully produce reactive-oxygen-species (ROS) and are found in most kingdoms of life. The seven human NOXs are each characterized by a specific expression profile and a fine regulation to spatio-temporally tune ROS concentration in cells and tissues. One of the best known...

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Bibliographic Details
Main Authors: Joana Reis, Marta Massari, Sara Marchese, Marta Ceccon, Friso S. Aalbers, Federica Corana, Sergio Valente, Antonello Mai, Francesca Magnani, Andrea Mattevi
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Redox Biology
Subjects:
NADPH oxidase
NOX
Reactive oxygen species
ROS scavengers
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231720301269

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http://www.sciencedirect.com/science/article/pii/S2213231720301269

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