Murine Embryonic Stem Cell-Derived Hepatic Progenitor Cells Engraft in Recipient Livers with Limited Capacity of Liver Tissue Formation

Murine Embryonic Stem Cell-Derived Hepatic Progenitor Cells Engraft in Recipient Livers with Limited Capacity of Liver Tissue Formation

Directed endodermal differentiation of murine embryonic stem (ES) cells gives rise to a subset of cells with a hepatic phenotype. Such ES cell-derived hepatic progenitor cells (ES-HPC) can acquire features of hepatocytes in vitro, but fail to form substantial hepatocyte clusters in vivo. In this stu...

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Bibliographic Details
Main Authors: Amar Deep Sharma, Tobias Cantz, Arndt Vogel, Axel Schambach, Dhivya Haridass, Markus Iken, Martina Bleidißel, Michael P. Manns, Hans R. Schöler, Michael Ott
Format: Article
Language:English
Published: SAGE Publishing 2008-03-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368908784153896

Internet

https://doi.org/10.3727/096368908784153896

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