Collagen fibrillogenesis in the development of the annulus fibrosus of the intervertebral disc

The annulus fibrosus of the intervertebral disc is a complex, radial-ply connective tissue consisting of concentric lamellae of oriented collagen. Whilst much is known of the structure of the mature annulus, less is known of how its complex collagenous architecture becomes established; an understand...

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Bibliographic Details
Main Authors: AJ Hayes, MD Isaacs, C Hughes, B Caterson, JR Ralphs
Format: Article
Language:English
Published: AO Research Institute Davos 2011-10-01
Series:European Cells & Materials
Subjects:
Online Access:http://www.ecmjournal.org/journal/papers/vol022/pdf/v022a18.pdf