Characterisation of mesothelioma-initiating cells and their susceptibility to anti-cancer agents.

Malignant mesothelioma (MM) is an aggressive type of tumour causing high mortality. One reason for this paradigm may be the existence of a subpopulation of tumour-initiating cells (TICs) that endow MM with drug resistance and recurrence. The objective of this study was to identify and characterise a...

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Main Authors: Elham Alizadeh Pasdar, Michael Smits, Michael Stapelberg, Martina Bajzikova, Marina Stantic, Jacob Goodwin, Bing Yan, Jan Stursa, Jaromira Kovarova, Karishma Sachaphibulkij, Ayenachew Bezawork-Geleta, Margaryta Sobol, Anatoly Filimonenko, Marco Tomasetti, Renata Zobalova, Pavel Hozak, Lan-Feng Dong, Jiri Neuzil
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4416766?pdf=render