Stress-Induced Anxiety- and Depressive-Like Phenotype Associated with Transient Reduction in Neurogenesis in Adult Nestin-CreERT2/Diphtheria Toxin Fragment A Transgenic Mice.

Stress-Induced Anxiety- and Depressive-Like Phenotype Associated with Transient Reduction in Neurogenesis in Adult Nestin-CreERT2/Diphtheria Toxin Fragment A Transgenic Mice.

Depression and anxiety involve hippocampal dysfunction, but the specific relationship between these mood disorders and adult hippocampal dentate gyrus neurogenesis remains unclear. In both humans with MDD and rodent models of depression, administration of antidepressants increases DG progenitor and...

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Bibliographic Details
Main Authors: Sanghee Yun, Michael H Donovan, Michele N Ross, Devon R Richardson, Robin Reister, Laure A Farnbauch, Stephanie J Fischer, Dieter Riethmacher, Howard K Gershenfeld, Diane C Lagace, Amelia J Eisch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4721672?pdf=render

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http://europepmc.org/articles/PMC4721672?pdf=render

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