Local Ancestry Inference in a Large US-Based Hispanic/Latino Study: Hispanic Community Health Study/Study of Latinos (HCHS/SOL)

Local Ancestry Inference in a Large US-Based Hispanic/Latino Study: Hispanic Community Health Study/Study of Latinos (HCHS/SOL)

We estimated local ancestry on the autosomes and X chromosome in a large US-based study of 12,793 Hispanic/Latino individuals using the RFMix method, and we compared different reference panels and approaches to local ancestry estimation on the X chromosome by means of Mendelian inconsistency rates a...

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Bibliographic Details
Main Authors: Sharon R. Browning, Kelsey Grinde, Anna Plantinga, Stephanie M. Gogarten, Adrienne M. Stilp, Robert C. Kaplan, M. Larissa Avilés-Santa, Brian L. Browning, Cathy C. Laurie
Format: Article
Language:English
Published: Oxford University Press 2016-06-01
Series:G3: Genes, Genomes, Genetics
Subjects:
Hispanic/Latino
local ancestry
principal components analysis
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.116.028779

Internet

http://g3journal.org/lookup/doi/10.1534/g3.116.028779

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