Methylation Status of the Adeno-Associated Virus Type 2 (AAV2)

Methylation Status of the Adeno-Associated Virus Type 2 (AAV2)

To analyze the methylation status of wild-type adeno-associated virus type 2 (AAV2), bisulfite PCR sequencing (BPS) of the packaged viral genome and its integrated form was performed and 262 of the total 266 CG dinucleotides (CpG) were mapped. In virion-packaged DNA, the ratio of the methylated cyto...

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Bibliographic Details
Main Authors: Renáta Tóth, István Mészáros, Daniela Hüser, Barbara Forró, Szilvia Marton, Ferenc Olasz, Krisztián Bányai, Regine Heilbronn, Zoltán Zádori
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Viruses
Subjects:
AAV2
adeno-associated virus
bisulfite PCR
CpG methylation
DNA virus
Parvoviridae
Online Access:http://www.mdpi.com/1999-4915/11/1/38

Internet

http://www.mdpi.com/1999-4915/11/1/38

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