Predicting effective microRNA target sites in mammalian mRNAs

MicroRNA targets are often recognized through pairing between the miRNA seed region and complementary sites within target mRNAs, but not all of these canonical sites are equally effective, and both computational and in vivo UV-crosslinking approaches suggest that many mRNAs are targeted through non-...

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Bibliographic Details
Main Authors: Vikram Agarwal, George W Bell, Jin-Wu Nam, David P Bartel
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-08-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/05005