Tumor DNA methylation profiles correlate with response to anti-PD-1 immune checkpoint inhibitor monotherapy in sarcoma patients

Tumor DNA methylation profiles correlate with response to anti-PD-1 immune checkpoint inhibitor monotherapy in sarcoma patients

Background Some sarcomas respond to immune checkpoint inhibition, but predictive biomarkers are unknown. We analyzed tumor DNA methylation profiles in relation to immunological parameters and response to anti-programmed cell death 1 (anti-PD-1) immune checkpoint inhibitor (ICI) therapy in patients w...

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Bibliographic Details
Main Authors: Matthias Preusser, Leonhard Müllauer, Anna S Berghoff, Sebastian Bauer, Gerwin Heller, Thomas Brodowicz, Wolfgang Lamm, Katharina Feldmann, Angelika M Starzer, Rainer Hamacher, Erwin Tomasich, Teresa Hatziioannou, Stefan Traint, Iris M Noebauer-Huhmann, Julia Furtner, Gabriele Amann, Hans-Ulrich Schildhaus
Format: Article
Language:English
Published: BMJ Publishing Group 2021-03-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/9/3/e001458.full

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https://jitc.bmj.com/content/9/3/e001458.full

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