Gene inactivation by CRISPR-Cas9 in Nicotiana tabacum BY-2 suspension cells

Gene inactivation by CRISPR-Cas9 in Nicotiana tabacum BY-2 suspension cells

Plant suspension cells are interesting hosts for the heterologous production of pharmacological proteins such as antibodies. They have the advantage to facilitate the containment and the application of good manufacturing practices (GMPs). Furthermore, antibodies can be secreted to the extracellular...

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Bibliographic Details
Main Authors: Sébastien eMercx, Jérémie eTollet, Bertrand eMagy, Catherine eNavarre, Marc eBoutry
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-02-01
Series:Frontiers in Plant Science
Subjects:
Gene Targeting
Plants
CRISPR
Gene inactivation
Cas9
Suspension cells
Online Access:http://journal.frontiersin.org/Journal/10.3389/fpls.2016.00040/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fpls.2016.00040/full

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