Intranasal delivery of VEGF enhances compensatory lung growth in mice.

Intranasal delivery of VEGF enhances compensatory lung growth in mice.

Vascular endothelial growth factor (VEGF) has previously been demonstrated to accelerate compensatory lung growth (CLG) in mice and may be a useful therapy for pulmonary hypoplasia. Systemic administration of VEGF can result in side effects such as hypotension and edema. The aim of this study was to...

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Bibliographic Details
Main Authors: Duy T Dao, Jacqueline T Vuong, Lorenzo Anez-Bustillos, Amy Pan, Paul D Mitchell, Gillian L Fell, Meredith A Baker, Diane R Bielenberg, Mark Puder
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5991715?pdf=render

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http://europepmc.org/articles/PMC5991715?pdf=render

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