High Betaine, a Trimethylamine N-Oxide Related Metabolite, Is Prospectively Associated with Low Future Risk of Type 2 Diabetes Mellitus in the PREVEND Study

High Betaine, a Trimethylamine N-Oxide Related Metabolite, Is Prospectively Associated with Low Future Risk of Type 2 Diabetes Mellitus in the PREVEND Study

Background: Gut microbiota-related metabolites, trimethylamine-N-oxide (TMAO), choline, and betaine, have been shown to be associated with cardiovascular disease (CVD) risk. Moreover, lower plasma betaine concentrations have been reported in subjects with type 2 diabetes mellitus (T2DM). However, fe...

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Bibliographic Details
Main Authors: Erwin Garcia, Maryse C. J. Osté, Dennis W. Bennett, Elias J. Jeyarajah, Irina Shalaurova, Eke G. Gruppen, Stanley L. Hazen, James D. Otvos, Stephan J. L. Bakker, Robin P.F. Dullaart, Margery A. Connelly
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Journal of Clinical Medicine
Subjects:
betaine
trimethylamine n-oxide related metabolites
nuclear magnetic resonance spectroscopy
type 2 diabetes mellitus
Online Access:https://www.mdpi.com/2077-0383/8/11/1813

Internet

https://www.mdpi.com/2077-0383/8/11/1813

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