PPAR-γ regulates carnitine homeostasis and mitochondrial function in a lamb model of increased pulmonary blood flow.

PPAR-γ regulates carnitine homeostasis and mitochondrial function in a lamb model of increased pulmonary blood flow.

<h4>Objective</h4>Carnitine homeostasis is disrupted in lambs with endothelial dysfunction secondary to increased pulmonary blood flow (Shunt). Our recent studies have also indicated that the disruption in carnitine homeostasis correlates with a decrease in PPAR-γ expression in Shunt lam...

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Bibliographic Details
Main Authors: Shruti Sharma, Xutong Sun, Ruslan Rafikov, Sanjiv Kumar, Yali Hou, Peter E Oishi, Sanjeev A Datar, Gary Raff, Jeffrey R Fineman, Stephen M Black
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22962578/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22962578/?tool=EBI

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