Microevolution of group A streptococci in vivo: capturing regulatory networks engaged in sociomicrobiology, niche adaptation, and hypervirulence.

The onset of infection and the switch from primary to secondary niches are dramatic environmental changes that not only alter bacterial transcriptional programs, but also perturb their sociomicrobiology, often driving minor subpopulations with mutant phenotypes to prevail in specific niches. Having...

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Bibliographic Details
Main Authors: Ramy K Aziz, Rita Kansal, Bruce J Aronow, William L Taylor, Sarah L Rowe, Michael Kubal, Gursharan S Chhatwal, Mark J Walker, Malak Kotb
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2854683?pdf=render