Identification of genetic determinants of the sexual dimorphism in CNS autoimmunity.

Multiple sclerosis (MS) is a debilitating chronic inflammatory disease of the nervous system that affects approximately 2.3 million individuals worldwide, with higher prevalence in females, and a strong genetic component. While over 200 MS susceptibility loci have been identified in GWAS, the underl...

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Bibliographic Details
Main Authors: Frank Bearoff, Laure K Case, Dimitry N Krementsov, Emma H Wall, Naresha Saligrama, Elizabeth P Blankenhorn, Cory Teuscher
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4324900?pdf=render