NLRP3 inflammasome and its inhibitors: a review

Inflammasomes are newly recognized, vital players in innate immunity. The best characterized is the NLRP3 inflammasome, so-called because the NLRP3 protein in the complex belongs to the family of nucleotide-binding and oligomerization domain-like receptors (NLRs) and is also known as pyrin domain-co...

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Bibliographic Details
Main Authors: Bo-Zong eShao, Zhe-qi eXu, Bin-Ze eHan, Ding-Feng eSu, Chong eLiu
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-11-01
Series:Frontiers in Pharmacology
Subjects:
BHB
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00262/full