Quantitative mapping of transcriptome and proteome dynamics during polarization of human iPSC-derived neurons

Quantitative mapping of transcriptome and proteome dynamics during polarization of human iPSC-derived neurons

The differentiation of neuronal stem cells into polarized neurons is a well-coordinated process which has mostly been studied in classical non-human model systems, but to what extent these findings are recapitulated in human neurons remains unclear. To study neuronal polarization in human neurons, w...

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Bibliographic Details
Main Authors: Feline W Lindhout, Robbelien Kooistra, Sybren Portegies, Lotte J Herstel, Riccardo Stucchi, Basten L Snoek, AF Maarten Altelaar, Harold D MacGillavry, Corette J Wierenga, Casper C Hoogenraad
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-09-01
Series:eLife
Subjects:
hiPSC-derived neuron
transcriptome
proteome
development
polarity
axon
Online Access:https://elifesciences.org/articles/58124

Internet

https://elifesciences.org/articles/58124

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