α1-Adrenergic Receptor Blockade by Prazosin Synergistically Stabilizes Rat Peritoneal Mast Cells

Background. Adrenaline quickly inhibits the release of histamine from mast cells. Besides β2-adrenergic receptors, several in vitro studies also indicate the involvement of α-adrenergic receptors in the process of exocytosis. Since exocytosis in mast cells can be detected electrophysiologically by t...

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Bibliographic Details
Main Authors: Nozomu Abe, Hiroaki Toyama, Yutaka Ejima, Kazutomo Saito, Tsutomu Tamada, Masanori Yamauchi, Itsuro Kazama
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2020/3214186