MutationalPatterns: comprehensive genome-wide analysis of mutational processes

MutationalPatterns: comprehensive genome-wide analysis of mutational processes

Abstract Background Base substitution catalogues represent historical records of mutational processes that have been active in a cell. Such processes can be distinguished by various characteristics, like mutation type, sequence context, transcriptional and replicative strand bias, genomic distributi...

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Bibliographic Details
Main Authors: Francis Blokzijl, Roel Janssen, Ruben van Boxtel, Edwin Cuppen
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Genome Medicine
Subjects:
R
Base substitutions
Somatic mutations
Mutational signatures
Mutational processes
Transcriptional strand bias
Online Access:http://link.springer.com/article/10.1186/s13073-018-0539-0

Internet

http://link.springer.com/article/10.1186/s13073-018-0539-0

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