Wheat germ and vitamin E decrease BAX/BCL-2 ratio in rat kidney treated with gentamicin
The intracellular accumulation of gentamicin acts on mitochondria directly (by increasing oxidative stress) and indirectly (by increasing the proapoptotic BAX gene expression levels) and thus activates intrinsic pathway of apoptosis. This study intended to investigate the probable prophylactic effec...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SpringerOpen
2018-09-01
|
| Series: | Beni-Suef University Journal of Basic and Applied Sciences |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2314853517304110 |