HSP70 of Leishmania amazonensis alters resistance to different stresses and mitochondrial bioenergetics

HSP70 of Leishmania amazonensis alters resistance to different stresses and mitochondrial bioenergetics

The 70 kDa heat shock protein (HSP70) is a molecular chaperone that assists the parasite Leishmania in returning to homeostasis after being subjected to different types of stress during its life cycle. In the present study, we evaluated the effects of HSP70 transfection of L. amazonensis promastigot...

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Bibliographic Details
Main Authors: Bárbara Santoni Codonho, Solange dos Santos Costa, Eduardo de Figueiredo Peloso, Paulo Pinto Joazeiro, Fernanda Ramos Gadelha, Selma Giorgio
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2016-01-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
Leishmania amazonensis
HSP70
mitochondria
oxidative stress
hyperbaric oxygen
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762016005001103&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762016005001103&lng=en&tlng=en

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