Metformin - its anti-cancer effects in hematologic malignancies
The main anti-diabetic effect of metformin mediated through stimulation of adenosine monophosphate (AMP)-activated protein kinase (AMPK) is the inhibition of hepatic gluconeogenesis and triggering glucose uptake in skeletal muscles. Additionally, some new pathways, besides the AMPK activation, were...
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| Format: | Article |
| Language: | English |
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PAGEPress Publications
2021-02-01
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| Series: | Oncology Reviews |
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| Online Access: | https://oncologyreviews.org/site/article/view/514 |