Developmentally Regulated Innate Immune NFκB Signaling Mediates IL-1α Expression in the Perinatal Murine Lung

Developmentally Regulated Innate Immune NFκB Signaling Mediates IL-1α Expression in the Perinatal Murine Lung

Bronchopulmonary dysplasia (BPD) is the most common morbidity complicating premature birth. Importantly, preclinical models have demonstrated that IL-1 receptor antagonism prevents the lung injury and subsequent abnormal development that typically results following perinatal exposure to inflammatory...

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Bibliographic Details
Main Authors: Brittany Butler, Robyn De Dios, Leanna Nguyen, Sarah McKenna, Sankar Ghosh, Clyde J. Wright
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Immunology
Subjects:
rodent
endotoxin shock
inflammation
signal transduction
lung
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01555/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01555/full

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