Spatial analysis improves the detection of early corneal nerve fiber loss in patients with recently diagnosed type 2 diabetes.

Spatial analysis improves the detection of early corneal nerve fiber loss in patients with recently diagnosed type 2 diabetes.

Corneal confocal microscopy (CCM) has revealed reduced corneal nerve fiber (CNF) length and density (CNFL, CNFD) in patients with diabetes, but the spatial pattern of CNF loss has not been studied. We aimed to determine whether spatial analysis of the distribution of corneal nerve branching points (...

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Bibliographic Details
Main Authors: Dan Ziegler, Karsten Winter, Alexander Strom, Andrey Zhivov, Stephan Allgeier, Nikolaos Papanas, Iris Ziegler, Jutta Brüggemann, Bernd Ringel, Sabine Peschel, Bernd Köhler, Oliver Stachs, Rudolf F Guthoff, Michael Roden, German Diabetes Study (GDS) Group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5352008?pdf=render

Internet

http://europepmc.org/articles/PMC5352008?pdf=render

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