DGAT1 overexpression in muscle by in vivo DNA electroporation increases intramyocellular lipid content

DGAT1 overexpression in muscle by in vivo DNA electroporation increases intramyocellular lipid content

In adipose tissue, the microsomal enzyme 1,2-acyl CoA:diacylglyceroltransferase-1 (DGAT1) plays an important role in triglyceride storage. Because DGAT1 is expressed in skeletal muscle as well, we aimed to directly test the effect of DGAT1 on muscular triglyceride storage by overexpressing DGAT1 usi...

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Bibliographic Details
Main Authors: Berber D. Roorda, Matthijs K.C. Hesselink, Gert Schaart, Esther Moonen-Kornips, Pilar Martínez-Martínez, Mario Losen, Marc H. De Baets, Ronald P. Mensink, Patrick Schrauwen
Format: Article
Language:English
Published: Elsevier 2005-02-01
Series:Journal of Lipid Research
Subjects:
1,2-acyl CoA:diacylglyceroltransferase-1
muscle
intramyocellular lipid
gene transfer
high-fat diet
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520340554

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http://www.sciencedirect.com/science/article/pii/S0022227520340554

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