Shikonin Reduces Growth of Docetaxel-Resistant Prostate Cancer Cells Mainly through Necroptosis

Shikonin Reduces Growth of Docetaxel-Resistant Prostate Cancer Cells Mainly through Necroptosis

The prognosis for advanced prostate carcinoma (PCa) remains poor due to development of therapy resistance, and new treatment options are needed. Shikonin (SHI) from Traditional Chinese Medicine has induced antitumor effects in diverse tumor entities, but data related to PCa are scarce. Therefore, th...

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Bibliographic Details
Main Authors: Sascha D. Markowitsch, Kira M. Juetter, Patricia Schupp, Kristine Hauschulte, Olesya Vakhrusheva, Kimberly Sue Slade, Anita Thomas, Igor Tsaur, Jindrich Cinatl, Martin Michaelis, Thomas Efferth, Axel Haferkamp, Eva Juengel
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cancers
Subjects:
prostate cancer (PCa)
docetaxel (DX) resistance
shikonin (SHI)
Traditional Chinese Medicine (TCM)
growth inhibition
apoptosis
Online Access:https://www.mdpi.com/2072-6694/13/4/882

Internet

https://www.mdpi.com/2072-6694/13/4/882

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