Anti-Inflammatory Effects of Curvularin-Type Metabolites from a Marine-Derived Fungal Strain Penicillium sp. SF-5859 in Lipopolysaccharide-Induced RAW264.7 Macrophages

Anti-Inflammatory Effects of Curvularin-Type Metabolites from a Marine-Derived Fungal Strain Penicillium sp. SF-5859 in Lipopolysaccharide-Induced RAW264.7 Macrophages

Chemical study on the extract of a marine-derived fungal strain Penicillium sp. SF-5859 yielded a new curvularin derivative (1), along with eight known curvularin-type polyketides (2–9). The structures of these metabolites (1–9) were established by comprehensive spectroscopic analyses, including 1D...

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Bibliographic Details
Main Authors: Tran Minh Ha, Wonmin Ko, Seung Jun Lee, Youn-Chul Kim, Jae-Young Son, Jae Hak Sohn, Joung Han Yim, Hyuncheol Oh
Format: Article
Language:English
Published: MDPI AG 2017-09-01
Series:Marine Drugs
Subjects:
curvularin-type metabolites
marine-derived fungus
anti-inflammatory effects
nuclear factor kappa B
Online Access:https://www.mdpi.com/1660-3397/15/9/282

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https://www.mdpi.com/1660-3397/15/9/282

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