Antiviral therapy: Inhibition of Hepatitis C Virus expression by RNA interference directed against the NS5B region of the Viral Genome

Antiviral therapy: Inhibition of Hepatitis C Virus expression by RNA interference directed against the NS5B region of the Viral Genome

Background: Hepatitis C virus (HCV) is a major public health problem with 170 million chronically infected people throughout the world. Currently, the only treatment available consists of a combination of pegylated interferon (INF-a) and ribavirin, but only half of the patients treated show a suffic...

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Bibliographic Details
Main Authors: Laura Trejo-Ávila;, Regina Elizondo-González;, Karina del C. Trujillo-Murillo;, Pablo Zapata-Benavides;, Cristina Rodríguez-Padilla;, Ana María Rivas-Estilla
Format: Article
Language:English
Published: Elsevier 2007-07-01
Series:Annals of Hepatology
Subjects:
Hepatitis C virus (HCV)
RNA interference (RNAi)
small interfering RNA (siRNA)
non-structural 5B HCV protein (NS5B)
HCV ribonucleic acid (HCV-RNA).
Online Access:http://www.sciencedirect.com/science/article/pii/S1665268119319258

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http://www.sciencedirect.com/science/article/pii/S1665268119319258

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