Efficient Neuroprotective Rescue of Sacsin-Related Disease Phenotypes in Zebrafish

Efficient Neuroprotective Rescue of Sacsin-Related Disease Phenotypes in Zebrafish

Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is a multisystem hereditary ataxia associated with mutations in <i>SACS</i>, which encodes sacsin, a protein of still only partially understood function. Although mouse models of ARSACS mimic largely the disease progressi...

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Bibliographic Details
Main Authors: Valentina Naef, Maria Marchese, Asahi Ogi, Gianluca Fichi, Daniele Galatolo, Rosario Licitra, Stefano Doccini, Tiziano Verri, Francesco Argenton, Federica Morani, Filippo M. Santorelli
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
ARSACS
ataxia
cerebellum
neurological disorders
zebrafish
Online Access:https://www.mdpi.com/1422-0067/22/16/8401

Internet

https://www.mdpi.com/1422-0067/22/16/8401

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