Efficient Neuroprotective Rescue of Sacsin-Related Disease Phenotypes in Zebrafish
Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is a multisystem hereditary ataxia associated with mutations in <i>SACS</i>, which encodes sacsin, a protein of still only partially understood function. Although mouse models of ARSACS mimic largely the disease progressi...
Main Authors: | Valentina Naef, Maria Marchese, Asahi Ogi, Gianluca Fichi, Daniele Galatolo, Rosario Licitra, Stefano Doccini, Tiziano Verri, Francesco Argenton, Federica Morani, Filippo M. Santorelli |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-08-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/22/16/8401 |
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