Da-Chai-Hu Decoction Ameliorates High Fat Diet-Induced Nonalcoholic Fatty Liver Disease Through Remodeling the Gut Microbiota and Modulating the Serum Metabolism

Da-Chai-Hu Decoction Ameliorates High Fat Diet-Induced Nonalcoholic Fatty Liver Disease Through Remodeling the Gut Microbiota and Modulating the Serum Metabolism

The dysbiosis in gut microbiota could affect host metabolism and contribute to the development of nonalcoholic fatty liver disease (NAFLD). Da-Chai-Hu decoction (DCH) has demonstrated protective effects on NAFLD, however, the exact mechanisms remain unclear. In this study, we established a NAFLD rat...

Full description

Bibliographic Details
Main Authors: Huantian Cui, Yuting Li, Yuming Wang, Lulu Jin, Lu Yang, Li Wang, Jiabao Liao, Haoshuo Wang, Yanfei Peng, Zhaiyi Zhang, Hongwu Wang, Xiangguo Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Pharmacology
Subjects:
nonalcoholic fatty liver disease
Da-Chai-Hu decoction
gut microbiota
untargeted metabolomics
correlation analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.584090/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2020.584090/full

Similar Items