Oxidants in the Gas Phase of Cigarette Smoke Pass Through the Lung Alveolar Wall and Raise Systemic Oxidative Stress

Cigarette smoking-induced oxidative stress plays a key role in the pathogenesis of atherosclerosis in smokers. Aqueous cigarette smoke extract (CSE) contains stable oxidants, peroxynitrite-like reactants, which have the ability to oxidize and nitrate low-density lipoprotein (LDL). We examined whethe...

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Bibliographic Details
Main Authors: Yu Yamaguchi, Fumiko Nasu, Atsuko Harada, Masaru Kunitomo
Format: Article
Language:English
Published: Elsevier 2007-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319343051