Improved radiolabeling of DOTATOC with trivalent radiometals for clinical application by addition of ethanol

Improved radiolabeling of DOTATOC with trivalent radiometals for clinical application by addition of ethanol

Abstract Background Typically, metal-based radiopharmaceuticals are synthesized in aqueous solutions with no or low ethanol content. Labeling yields are defined by temperature, period of labeling, amount of precursor, pH etc. As recently observed, radiolabeling yields (RCY) seem to increase in the p...

Full description

Bibliographic Details
Main Authors: Elisabeth Eppard, Marylaine Pèrez-Malo, Frank Rösch
Format: Article
Language:English
Published: SpringerOpen 2016-04-01
Series:EJNMMI Radiopharmacy and Chemistry
Subjects:
DOTATOC
Ethanol
Radiolabeling
Radiopharmaceuticals
Kit
Online Access:http://link.springer.com/article/10.1186/s41181-016-0010-8

Internet

http://link.springer.com/article/10.1186/s41181-016-0010-8

Similar Items