Esmolol infusion in patients with septic shock and tachycardia: a prospective, single-arm, feasibility study

Esmolol infusion in patients with septic shock and tachycardia: a prospective, single-arm, feasibility study

Abstract Background High adrenergic tone appears to be associated with mortality in septic shock, while adrenergic antagonism may improve survival. In preparation for a randomized trial, we conducted a prospective, single-arm pilot study of esmolol infusion for patients with septic shock and tachyca...

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Main Authors: Samuel M. Brown, Sarah J. Beesley, Michael J. Lanspa, Colin K. Grissom, Emily L. Wilson, Samir M. Parikh, Todd Sarge, Daniel Talmor, Valerie Banner-Goodspeed, Victor Novack, B. Taylor Thompson, Sajid Shahul, The Esmolol to Control Adrenergic Storm in Septic Shock-ROLL-IN (ECASSS-R) study
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Pilot and Feasibility Studies
Subjects:
Sepsis
Beta blockade
Adrenergic antagonism
Clinical trial
Heart rate variability
Organ-failure-free days
Online Access:http://link.springer.com/article/10.1186/s40814-018-0321-5

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http://link.springer.com/article/10.1186/s40814-018-0321-5

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