Quercetin through mitigation of inflammatory response and oxidative stress exerts protective effects in rat model of diclofenac-induced liver toxicity

Quercetin through mitigation of inflammatory response and oxidative stress exerts protective effects in rat model of diclofenac-induced liver toxicity

Context: Diclofenac (DIC) is known for its anti-inflammatory and analgesic properties but liver toxicity is one of the main targets to use this drug. Previous studies have demonstrated that quercetin may decrease the toxicity of synthetic drugs. Aim: To assess the protective effect of quercetin a...

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Bibliographic Details
Main Authors: Ali Nouri, Esfandiar Heidarian, Hossein Amini-khoei, Saber Abbaszadeh, Gholam Basati
Format: Article
Language:English
Published: Academic Association of Pharmaceutical Sciences from Antofagasta (ASOCIFA) 2019-05-01
Series:Journal of Pharmacy & Pharmacognosy Research
Subjects:
diclofenac
IL-1β
liver toxicity
oxidative stress
quercetin
TNF-α
Online Access:http://jppres.com/jppres/pdf/vol7/jppres19.610_7.3.200.pdf

Internet

http://jppres.com/jppres/pdf/vol7/jppres19.610_7.3.200.pdf

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