Targeting fatty acid binding protein (FABP) anandamide transporters - a novel strategy for development of anti-inflammatory and anti-nociceptive drugs.

Targeting fatty acid binding protein (FABP) anandamide transporters - a novel strategy for development of anti-inflammatory and anti-nociceptive drugs.

Fatty acid binding proteins (FABPs), in particular FABP5 and FABP7, have recently been identified by us as intracellular transporters for the endocannabinoid anandamide (AEA). Furthermore, animal studies by others have shown that elevated levels of endocannabinoids resulted in beneficial pharmacolog...

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Bibliographic Details
Main Authors: William T Berger, Brian P Ralph, Martin Kaczocha, Jing Sun, Trent E Balius, Robert C Rizzo, Samir Haj-Dahmane, Iwao Ojima, Dale G Deutsch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3517626?pdf=render

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http://europepmc.org/articles/PMC3517626?pdf=render

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