Generation of two induced pluripotent stem cell (iPSC) lines from human breast milk using episomal reprogramming system

Human breast milk epithelial cells (BMECs) can be isolated and cultured with high purity. Induced pluripotent stem cells (iPSCs) were generated from BMECs with Yamanaka factors (OCT4, SOX2, c-MYC, KLF4) using episomal system. Pluripotency of breast milk-derived iPSCs (BM-iPSCs) was confirmed by the...

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Bibliographic Details
Main Authors: Chuanqing Tang, Chunmei Lu, Xiaoli Ji, Ling Ma, Qi Zhou, Man Xiong, Wenhao Zhou
Format: Article
Language:English
Published: Elsevier 2019-08-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506119301412