Putative functions of extracellular matrix glycoproteins in secondary palate morphogenesis

Putative functions of extracellular matrix glycoproteins in secondary palate morphogenesis

Cleft palate is a common birth defect in humans. Elevation and fusion of paired palatal shelves are coordinated by growth and transcription factors, and mutations in these can cause malformations. Among the effector genes for growth factor signaling are extracellular matrix (ECM) glycoproteins. Thes...

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Bibliographic Details
Main Authors: Rocca ed'Amaro, Rolf eScheidegger, Susan eBlumer, Pawel ePazera, Christos eKatsaros, Daniel eGraf, Matthias eChiquet
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-09-01
Series:Frontiers in Physiology
Subjects:
Extracellular Matrix
Tenascin
Transforming Growth Factor beta
growth factors
fibronectin
Palate morphogenesis
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00377/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00377/full

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