Reversal of metabolic disorders by pharmacological activation of bile acid receptors TGR5 and FXR

Reversal of metabolic disorders by pharmacological activation of bile acid receptors TGR5 and FXR

Objectives: Activation of the bile acid (BA) receptors farnesoid X receptor (FXR) or G protein-coupled bile acid receptor (GPBAR1; TGR5) improves metabolic homeostasis. In this study, we aim to determine the impact of pharmacological activation of bile acid receptors by INT-767 on reversal of diet-i...

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Main Authors: Kavita Jadhav, Yang Xu, Yanyong Xu, Yuanyuan Li, Jiesi Xu, Yingdong Zhu, Luciano Adorini, Yoon Kwang Lee, Takhar Kasumov, Liya Yin, Yanqiao Zhang
Format: Article
Language:English
Published: Elsevier 2018-03-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877817309195

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http://www.sciencedirect.com/science/article/pii/S2212877817309195

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