Zika virus NS2A inhibits interferon signaling by degradation of STAT1 and STAT2

Zika virus NS2A inhibits interferon signaling by degradation of STAT1 and STAT2

The Interferon (IFN) response is crucial to restrain pathogenic infections. Investigations into flavivirus-host interactions reported that the high virulence is linked to innate immune evasion. Zika Virus (ZIKV) has developed diversified strategies to evade the innate immune system. We report that t...

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Bibliographic Details
Main Authors: Elisa Fanunza, Fabrizio Carletti, Marina Quartu, Nicole Grandi, Laura Ermellino, Jessica Milia, Angela Corona, Maria Rosaria Capobianchi, Giuseppe Ippolito, Enzo Tramontano
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Virulence
Subjects:
zika virus
ns2a
interferon
ifn signaling
ifn evasion
stat1
stat2
degradation
phosphorylation
Online Access:http://dx.doi.org/10.1080/21505594.2021.1935613

Internet

http://dx.doi.org/10.1080/21505594.2021.1935613

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