A mitochondrial strategy for safeguarding the reprogrammed genome

Genomic aberrations induced by somatic cell reprogramming are a major drawback for future applications of this technology in regenerative medicine. A new study by Ji et al. published in Stem Cell Reports suggests a counteracting strategy based on balancing the mitochondrial/oxidative stress pathway...

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Bibliographic Details
Main Authors: Alessandro Prigione, James Adjaye
Format: Article
Language:English
Published: SpringerOpen 2014-01-01
Series:Cell Regeneration
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2045976917300214