DNA methylation in Hepatoblastoma-a literature review

DNA methylation in Hepatoblastoma-a literature review

Abstract Hepatoblastoma (HB) is the most common malignant liver tumor in children. Abnormal activation of the Wnt/β-catenin signaling pathway plays an important role in the formation and development of HB. Genes in HB show a global hypomethylation change, accompanied by hypermethylation of specific...

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Bibliographic Details
Main Authors: Gang Shen, Hongyu Shen, Jing Zhang, Qingtao Yan, Huixian Liu
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Italian Journal of Pediatrics
Subjects:
Methylation
Hepatoblastoma
DNMTs
TETs
UHRF
Online Access:http://link.springer.com/article/10.1186/s13052-020-00877-6

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http://link.springer.com/article/10.1186/s13052-020-00877-6

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