The Orphan Nuclear Receptor Gene NR0B2 Is a Favorite Prognosis Factor Modulated by Multiple Cellular Signal Pathways in Human Liver Cancers

The Orphan Nuclear Receptor Gene NR0B2 Is a Favorite Prognosis Factor Modulated by Multiple Cellular Signal Pathways in Human Liver Cancers

BackgroundLiver cancer is a leading cause of cancer death worldwide, and novel prognostic factor is needed for early detection and therapeutic responsiveness monitoring. The orphan nuclear receptor NR0B2 was reported to suppress liver cancer development in a mouse model, and its expression levels we...

Full description

Bibliographic Details
Main Authors: Runzhi Zhu, Yanjie Tu, Jingxia Chang, Haixia Xu, Jean C. Li, Wang Liu, Ahn-Dao Do, Yuxia Zhang, Jinhu Wang, Benyi Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Oncology
Subjects:
NR0B2
liver cancer
survival
PI3K - AKT pathway
MAPK (ERK1/ERK2)
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.691199/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.691199/full

Similar Items