Effects of local and spinal administrations of mu-opioids on postoperative pain in aged vs adult mice
Abstract. Introduction:. Suboptimal management of postoperative pain leads to increased risk of chronic opioid therapy, especially in elderly patients. Objectives:. Although this age-dependent phenomenon has been observed clinically, basic mechanisms including baseline nociception, postoperative hyp...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer
2017-02-01
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| Series: | PAIN Reports |
| Online Access: | http://journals.lww.com/painrpts/fulltext/10.1097/PR9.0000000000000584 |