Differentially Altered NMDAR Dependent and Independent Long-Term Potentiation in the CA3 Subfield in a Model of Anti-NMDAR Encephalitis

Differentially Altered NMDAR Dependent and Independent Long-Term Potentiation in the CA3 Subfield in a Model of Anti-NMDAR Encephalitis

Purpose: Autoantibodies against NMDA receptors (NMDAR) in the cerebrospinal fluid (CSF) from anti-NMDAR encephalitis patients have been suggested to be pathogenic since in previous studies using patient CSF, NMDAR-dependent processes such as long-term potentiation (LTP) were compromised. However, au...

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Bibliographic Details
Main Authors: Roman Blome, Willi Bach, Xiati Guli, Katrin Porath, Tina Sellmann, Christian G. Bien, Rüdiger Köhling, Timo Kirschstein
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Synaptic Neuroscience
Subjects:
associational-commissural fibers
mossy fibers
LTP
NMDA receptor
epileptiform afterpotentials
Online Access:https://www.frontiersin.org/article/10.3389/fnsyn.2018.00026/full

Internet

https://www.frontiersin.org/article/10.3389/fnsyn.2018.00026/full

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